2025-02-12
- Neurotransmitter receptors are key proteins in neuronal communication that detect chemical signals and translate those into cellular responses to regulate a variety of biological processes.
- Many of these work as ionic channels activated by ligands and their aminoacid (Aa) sequence determines properties as ion selectivity, channel gating dynamics or subunit organization.
- Some Aa have strong influence on the structure and function of the receptors, favoring the recognition of the ligand and channel activation.
- Understanding these principles, a relation between Aa sequences and type of receptor can be found.
The dataset consist on a curated collection of neurotransmitter receptors from different organisms, as well as data regarding their composition, chemical properties and structural and functional characterization.
Combine via .row_id
aa_*) as featuresProtein_Name as target
Sys-loop Receptor
Ionotropic Glutamate Receptor